Michael Clarke (Calabar) The decision is a retrograde one and I hope it is a move in the right direction. On the other hand, they could see it as a progressive step as they are thinking about the future for these athletes and they are thinking of the participation of more students at these Championships. Danny Hawthorne (Wolmer’s Boys’ School) From a health-wise perspective, I think this is a good decision as the principals are thinking about the protection of the athletes. This will not affect our team as we are in the building process and with this it will help in maximising the efforts of more students. David Riley (Excelsior High) The principals have made their decision and we just have to work with it. This will not affect my team adversely as we are always working on developing athletes, especially in hurdling. The timing could have been better but we will just have to proceed and do what we have to do by producing good athletes. John Mair (Vere Technical) The timing is bad to implement these changes in the middle of the season and will definitely affect my team especially in the sprints. If you can’t beat them you have to join them and I am not surprised with the decision as coaches have no say on what goes on and are not given any respect. Michael Dyke (Edwin Allen High) I think more time should have been given to sensitise the coaches. However, a decision has been made and we have to work with it. This will definitely help bigger teams like mine and it will also help with more participation and more athletes will be given a chance to compete. This is difficult for the smaller teams which usually have limited athletes to maximise with and I am hoping this decision will not affect the quality of performances going forward.
Garbage collectors deadlockThe decision of Central Government to bail out City Hall from debts owed to two main solid waste collectors in the new year remains unfulfilled and there has been no contact between the two parties on the way forward.The two major solid waste collectorsSpeaking with Guyana Times on Wednesday, General Manager of Puran Brother’s Disposal Services, Khalesh Puran explained that no payments were made on behalf of the Government for services to resume.“There is still no payment from them or any date that these payments will be made,” said Puran.Without a date, collectors are questioning if they will be paid within the first week of January as was promised. Business Development Supervisor of Cevon Waste Management, Morris Archer had informed this media outlet that this was the assurance given.At that time, high hopes were beaming as expectations suggested that they would receive owed payments.On November 25, 2018, the collectors withdrew their services after examining the feasibility of operating without payments and being owed for over six months. Immediately after, services were provided by five agencies; namely Granderson, Trash Tech, Tri Star, C&S Services and Garbage Eaters.By the first week in December, Communities Minister Ronald Bulkan met with the collectors and officials of City Hall, where it was declared that Central Government would stand the outstanding $160 million by the ending of 2018.“It yielded what we believe to be credible assurances that settlement of the outstanding debt will commence very shortly. Our understanding is that the first payment will be made before the end of 2018. We have, without prejudice, accepted those assurances,” the service providers jointly announced.Meanwhile, buildups of waste across business enterprises and residential communities proved that the contractors were essential and further, that the smaller contractors were unable to service the entire city.For this, the contractor proposed to resume operations immediately with confirmation from the M&CC. This did not materialise to which they issued another statement, affirming that services would not be provided without credible assurances.“Timely payment under the terms of our contract with the Georgetown City Council is a fundamental issue. We cannot, we submit, be expected to provide services without reasonable assurances of timely payment. Where there is slippage we are prepared, as we have, over time, to exercise some measure of understanding to an extent that is reasonable.”
http://news.rice.edu/files/2016/09/0922_ANTIOXIDANT-1-WEB-qnb9wm.jpgDark spots in the mitochondria of a T lymphocyte cell are antioxidant nanoparticles created at Rice University and tested at Baylor College of Medicine. The nanoparticles are selectively taken up by T lymphocyte cells, which inhibits their activity and may help control symptoms for patients with autoimmune diseases like multiple sclerosis. (Credit: Redwan Huq and Debra Townley/Baylor College of Medicine) http://news.rice.edu/files/2016/09/0922_ANTIOXIDANT-3-web-11fov4e.jpgPolyethylene glycol-hydrophilic carbon clusters developed at Rice University were shown to be selectively taken up by T cells, which inhibits their function, in tests at Baylor College of Medicine. The researchers said the nanoparticles could lead to new strategies for controlling autoimmune diseases like multiple sclerosis. (Credit: Errol Samuel/Rice University)Located on a 300-acre forested campus in Houston, Rice University is consistently ranked among the nation’s top 20 universities by U.S. News & World Report. Rice has highly respected schools of Architecture, Business, Continuing Studies, Engineering, Humanities, Music, Natural Sciences and Social Sciences and is home to the Baker Institute for Public Policy. With 3,910 undergraduates and 2,809 graduate students, Rice’s undergraduate student-to-faculty ratio is 6-to-1. Its residential college system builds close-knit communities and lifelong friendships, just one reason why Rice is ranked No. 1 for happiest students and for lots of race/class interaction by the Princeton Review. Rice is also rated as a best value among private universities by Kiplinger’s Personal Finance. To read “What they’re saying about Rice,” go to http://tinyurl.com/RiceUniversityoverview. http://news.rice.edu/files/2016/09/0922_ANTIOXIDANT-2-WEB-125ikr9.jpgBaylor College of Medicine researchers Redwan Huq, left, and Christine Beeton. (Credit: Baylor College of Medicine/Agapito Sánchez Jr.) AddThis Share34Editor’s note: Links to high-resolution images for download appear at the end of this release. AT RICE UNIVERSITY:David Ruth713firstname.lastname@example.orgMike Williams713email@example.comAT BAYLOR COLLEGE OF MEDICINE:Graciela Gutierrez713firstname.lastname@example.orgTattoo therapy could ease chronic disease Rice-made nanoparticles tested at Baylor College of Medicine may help control autoimmune diseases HOUSTON – (Sept. 22, 2016) – A temporary tattoo to help control a chronic disease might someday be possible, according to scientists at Baylor College of Medicine who tested antioxidant nanoparticles created at Rice University.A proof-of-principle study led by Baylor scientist Christine Beeton published today by Nature’s online, open-access journal Scientific Reports shows that nanoparticles modified with polyethylene glycol are conveniently choosy as they are taken up by cells in the immune system.That could be a plus for patients with autoimmune diseases like multiple sclerosis, one focus of study at the Beeton lab. “Placed just under the skin, the carbon-based particles form a dark spot that fades over about one week as they are slowly released into the circulation,” Beeton said.T and B lymphocyte cells and macrophages are key components of the immune system. However, in many autoimmune diseases such as multiple sclerosis, T cells are the key players. One suspected cause is that T cells lose their ability to distinguish between invaders and healthy tissue and attack both.In tests at Baylor, nanoparticles were internalized by T cells, which inhibited their function, but ignored by macrophages. “The ability to selectively inhibit one type of cell over others in the same environment may help doctors gain more control over autoimmune diseases,” Beeton said.“The majority of current treatments are general, broad-spectrum immunosuppressants,” said Redwan Huq, lead author of the study and a graduate student in the Beeton lab. “They’re going to affect all of these cells, but patients are exposed to side effects (ranging) from infections to increased chances of developing cancer. So we get excited when we see something new that could potentially enable selectivity.” Since the macrophages and other splenic immune cells are unaffected, most of a patient’s existing immune system remains intact, he said.The soluble nanoparticles synthesized by the Rice lab of chemist James Tour have shown no signs of acute toxicity in prior rodent studies, Huq said. They combine polyethylene glycol with hydrophilic carbon clusters, hence their name, PEG-HCCs. The carbon clusters are 35 nanometers long, 3 nanometers wide and an atom thick, and bulk up to about 100 nanometers in globular form with the addition of PEG. They have proven to be efficient scavengers of reactive oxygen species called superoxide molecules, which are expressed by cells the immune system uses to kill invading microorganisms.T cells use superoxide in a signaling step to become activated. PEG-HCCs remove this superoxide from the T cells, preventing their activation without killing the cells.Beeton became aware of PEG-HCCs during a presentation by former Baylor graduate student Taeko Inoue, a co-author of the new study. “As she talked, I was thinking, ‘That has to work in models of multiple sclerosis,’” Beeton said. “I didn’t have a good scientific rationale, but I asked for a small sample of PEG-HCCs to see if they affected immune cells.“We found they affected the T lymphocytes and not the other splenic immune cells, like the macrophages. It was completely unexpected,” she said.The Baylor lab’s tests on animal models showed that small amounts of PEG-HCCs injected under the skin are slowly taken up by T lymphocytes, where they collect and inhibit the cell’s function. They also found the nanoparticles did not remain in T cells and dispersed within days after uptake by the cells.“That’s an issue because you want a drug that’s in the system long enough to be effective, but not so long that, if you have a problem, you can’t remove it,” Beeton said. “PEG-HCCs can be administered for slow release and don’t stay in the system for long. This gives us much better control over the circulating half-life.”“The more we study the abilities of these nanoparticles, the more surprised we are at how useful they could be for medical applications,” Tour said. The Rice lab has published papers with collaborators at Baylor and elsewhere on using functionalized nanoparticles to deliver cancer drugs to tumors and to quench the overproduction of superoxides after traumatic brain injuries.Beeton suggested delivering carbon nanoparticles just under the skin rather than into the bloodstream would keep them in the system longer, making them more available for uptake by T cells. And the one drawback – a temporary but visible spot on the skin that looks like a tattoo – could actually be a perk to some.“We saw it made a black mark when we injected it, and at first we thought that’s going to be a real problem if we ever take it into the clinic,” Beeton said. “But we can work around that. We can inject into an area that’s hidden, or use micropattern needles and shape it.“I can see doing this for a child who wants a tattoo and could never get her parents to go along,” she said. “This will be a good way to convince them.”The research was supported by Baylor College of Medicine, the National Multiple Sclerosis Society, National Institutes of Health, the Dan L. Duncan Cancer Center, John S. Dunn Gulf Coast Consortium for Chemical Genomics and the U.S. Army-funded Traumatic Brain Injury Consortium.-30-Read the abstract at www.nature.com/articles/srep33808Follow Rice News and Media Relations via Twitter @RiceUNewsRelated materials:James Tour Group: http://www.jmtour.comChristine Beeton Lab: https://www.bcm.edu/research/labs/christine-beetonImages for download: